Bioproduction Group research has appeared in the May 2012 Bioprocess International magazine. The article, "Approaches to Debottlenecking and Process Optimization" details the shortcomings of traditional optimization in a facility setting - namely, that engineers are focused around their own small part of the process and unable to optimize the entire biomanufacturing process. The article examines how best in class biomanufacturers have used Bio-G toolsets to optimize metrics like throughput, cycle time, labor loading and WFI / utilitieis consumption, all in the presence of significant variability.